Tips for donors

Preparing your body for plasma donation: a comprehensive checklist

Tips for donors

Preparing your body for plasma donation: a comprehensive checklist

July 3, 2024

How can you best prepare for plasma donation? Here are a few simple rules to enhance your donation experience!

Plasma donation is a completely safe procedure. To make your experience even more efficient and comfortable, consider the following tips about nutrition, hydration, exercise, and rest to help prepare your body.

Woman holding a checklist

1. Essential nutritional tips for plasma donors

Eating well is crucial, not just on the day of the donation, but also in the days leading up to it. A well-balanced diet helps prepare your body for donation and supports quick recovery afterward. Consider integrating the following ingredients into your meals:

  • eat iron-rich foods, such as eggs, pulses, nuts, whole grains, iron-fortified cereals, and vegetables like spinach, arugula, cabbage, and kale
  • eat protein-rich foods, including fish, poultry, pulses, and milk.

Foods that are rich in protein and iron support plasma regeneration after every donation, making your recovery easier.

What you eat can affect the quality of your plasma, so it is best to avoid:

  • highly processed food, such as ready-made meals, savory and sweet snacks, and meat products like ham and sausage
  • food high in fat, for example, fries or fast food meals

In conclusion, a well-balanced and healthy diet will make you feel good before, during, and after your donation.

2. The importance of hydration before donating plasma

Since plasma is primarily composed of water (around 92%), proper hydration is key. Drinking enough water before and on the donation day will speed up the donation process and help you recover faster. Aim to drink at least 1.5 to 2 liters of water in the days leading up to your donation, including the donation day itself. Great sources of hydration are water, sugarless herbal teas, or homemade soups.

3. Recommended exercises for plasma donors

Regular, moderate exercise is beneficial for your overall health and helps ensure you are in good shape for donating plasma. However, avoid strenuous activities a few days before and on the donation day to ensure you are well-rested and healthy for your donation.  For a quick and smooth recovery, start off with light activities, such as walking, stretching, or yoga, before returning to your regular exercise routine.

4. Maximizing recovery: the impact of sleep on plasma donation

Get a good night’s sleep to help your body recover faster and manage the stress of the plasma donation. Arriving at the donation center rested and relaxed will help enhance your plasma donation experience.

A good night’s sleep also improves your blood pressure, which the donation center staff will check before the donation procedure.

5. What to Know About Medications Before Donating Plasma

Medical staff will check your health parameters on the day of your plasma donation and ask if you take any medication or supplements. Medications such as blood thinners can impact the quality of your plasma or temporarily disqualify you from donating. If in doubt, check with your healthcare provider to ensure you are clear to donate. 

6. Day-of Donation Tips

Here is a quick checklist to help you prepare for the day of your donation:

  • Unlike a blood test, you should eat a light, healthy, and nutritious meal before donating plasma.
  • Avoid smoking or drinking alcohol for at least 24 hours before donation.
  • Wear loose clothes with wide sleeves that you can roll up easily to be more comfortable during the procedure. 
  • Remember your ID: the staff will ask you for it when you arrive
  • Choose relaxing activities after the donation to avoid side effects and recover smoothly.

And remember, plasma replenishes within 24–48 hours, making it possible to donate frequently, but no more than once in a 48-hour period, to continue helping people in need of plasma-derived therapies!


Do you still have doubts about plasma donation? Our FAQs section will hopefully clear them up. Remember that our medical team and staff is always there to answer all your question in person.